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Corel Medical Series: Cancer
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c31.dxr
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00039_Field_SRC.c31.C.14.txt
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1997-01-28
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860b
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17 lines
Three-Year Survival 15 percent
Investigational
• Radiation given during the operation— intraoperative radiotherapy (IORT)—is being evaluated.
• Some trials of split course radiotherapy of 4,000 to 6,000 cGy over six to eight weeks have shown one-year
survival of 34 percent and five-year survival of 20 percent.
• Brachytherapy—implanting irradiating seeds of radon or boron—is under clinical evaluation at a few centers.
Results so far have not been promising.
• Postoperative large-field radiation with 5-FU chemotherapy is also being evaluated and it appears that this
combination improves survival. Side effects include diarrhea, inflammation of the intestinal lining and liver
toxicity.
Stage II
TNM T3, N0, M0
The cancer has directly spread to involve adjacent organs such as the stomach, spleen or colon.